Isoniazid resistance-conferring mutations are associated with highly variable phenotypic resistance
Background: High-dose isoniazid is recommended in the 9–12 months short-course regimen for multidrug-resistant tuberculosis with inhA mutation. However, there is insufficient evidence to support the assumption of genotypic-phenotypic concordance. This study aimed to identify the genetic mutations as...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | Journal of Clinical Tuberculosis and Other Mycobacterial Diseases |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405579423000438 |