CD82 palmitoylation site mutations at Cys5+Cys74 affect EGFR internalization and metabolism through recycling pathway

CD82 palmitoylation site mutations at Cys5+Cys74 affect EGFR internalization and metabolism through recycling pathway

Tetraspanin CD82 often participates in regulating the function of epidermal growth factor receptor (EGFR) and hepatocyte growth factor receptor (c-Met). Palmitoylation is a post-translational modification that contributes to tetraspanin web formation and affects tetraspanin-dependent cell signaling....

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Bibliographic Details
Main Authors: Bu Jingya, Zhong Weiliang, Li Meixian, He Shuiqing, Zhang Mingzhe, Zhang Yu, Li Ying
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-02-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
tetraspanin
CD82
palmitoylation
EGFR
Rab11a
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022011

Internet

https://www.sciengine.com/doi/10.3724/abbs.2022011

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