Membranolytic Activity Profile of Nonyl 3,4-Dihydroxybenzoate: A New Anti-Biofilm Compound for the Treatment of Dermatophytosis

Membranolytic Activity Profile of Nonyl 3,4-Dihydroxybenzoate: A New Anti-Biofilm Compound for the Treatment of Dermatophytosis

The ability of dermatophytes to live in communities and resist antifungal drugs may explain treatment recurrence, especially in onychomycosis. Therefore, new molecules with reduced toxicity that target dermatophyte biofilms should be investigated. This study evaluated nonyl 3,4-dihydroxybenzoate (no...

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Bibliographic Details
Main Authors: Caroline B. Costa-Orlandi, Níura M. Bila, Jean Lucas C. Bonatti, Carolina O. Vaso, Mariana B. Santos, Carlos R. Polaquini, Mariana M. Santoni Biasioli, Rondinelli D. Herculano, Luis O. Regasini, Ana Marisa Fusco-Almeida, Maria José S. Mendes-Giannini
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Pharmaceutics
Subjects:
dermatophytes
biofilms
anti-biofilm activity
antifungal drugs
mechanism of action
RT-PCR
Online Access:https://www.mdpi.com/1999-4923/15/5/1402

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https://www.mdpi.com/1999-4923/15/5/1402

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