Using phage to drive selections toward restoring antibiotic sensitivity in Pseudomonas aeruginosa via chromosomal deletions

Phage therapy has re-emerged in modern medicine as a robust antimicrobial strategy in response to the increasing prevalence of antimicrobial-resistant bacteria. However, bacterial resistance to phages can also arise via a variety of molecular mechanisms. In fact, several clinical studies on phage th...

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Bibliographic Details
Main Authors: Jumpei Fujiki, Keisuke Nakamura, Yuko Ishiguro, Hidetomo Iwano
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1401234/full