A Spatial Quantitative Systems Pharmacology Platform spQSP-IO for Simulations of Tumor–Immune Interactions and Effects of Checkpoint Inhibitor Immunotherapy

Quantitative systems pharmacology (QSP) models have become increasingly common in fundamental mechanistic studies and drug discovery in both academic and industrial environments. With imaging techniques widely adopted and other spatial quantification of tumor such as spatial transcriptomics gaining...

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Bibliographic Details
Main Authors: Chang Gong, Alvaro Ruiz-Martinez, Holly Kimko, Aleksander S. Popel
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/15/3751