The antimicrobial peptide Magainin-2 interacts with BamA impairing folding of E. coli membrane proteins

The antimicrobial peptide Magainin-2 interacts with BamA impairing folding of E. coli membrane proteins

Antimicrobial peptides (AMPs) are a unique and diverse group of molecules endowed with a broad spectrum of antibiotics properties that are being considered as new alternative therapeutic agents. Most of these peptides are membrane-active molecules, killing bacteria by membrane disruption. However, r...

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Bibliographic Details
Main Authors: Angela Di Somma, Carolina Cané, Antonio Moretta, Anna Illiano, Gabriella Pinto, Domenico Cavasso, Angela Amoresano, Luigi Paduano, Angela Duilio
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Chemistry
Subjects:
antimicrobial peptides
proteomics
membrane proteins
mechanism of action
structural and functional characterization
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.1013788/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2022.1013788/full

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