A Liposomal Formulation for Improving Solubility and Oral Bioavailability of Nifedipine

Proliposomes were used to improve the solubility and oral bioavailability of nifedipine. Nifedipine proliposomes were prepared by methanol injection-spray drying method. The response surface method was used to optimize formulation to enhance the encapsulation efficiency (EE%) of nifedipine. The part...

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Bibliographic Details
Main Authors: Ye Bi, Bingcong Lv, Lianlian Li, Robert J. Lee, Jing Xie, Zhidong Qiu, Lesheng Teng
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/2/338