The Angelica dahurica: A Review of Traditional Uses, Phytochemistry and Pharmacology
Angelica dahurica (A. dahurica) root is a famous edible medicinal herb that has been used in China for thousands of years. To date, more than 300 chemical constituents have been discovered from A. dahurica. Among these ingredients, coumarins and volatile oils are the major active compounds. Moreover...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-07-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2022.896637/full |
| _version_ | 1811227685587779584 |
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| author | Hui Zhao Hui Zhao Ya-Long Feng Ming Wang Jing-Jing Wang Tian Liu Tian Liu Jun Yu Jun Yu |
| author_facet | Hui Zhao Hui Zhao Ya-Long Feng Ming Wang Jing-Jing Wang Tian Liu Tian Liu Jun Yu Jun Yu |
| author_sort | Hui Zhao |
| collection | DOAJ |
| description | Angelica dahurica (A. dahurica) root is a famous edible medicinal herb that has been used in China for thousands of years. To date, more than 300 chemical constituents have been discovered from A. dahurica. Among these ingredients, coumarins and volatile oils are the major active compounds. Moreover, a few other compounds have also been isolated from the root of A. dahurica, such as alkaloids, phenols, sterols, benzofurans, polyacetylenes and polysaccharides. Modern pharmacological studies demonstrated that the root of A. dahurica and its active components displayed various bioactivities such as anti-inflammation, anti-tumor, anti-oxidation, analgesic activity, antiviral and anti-microbial effects, effects on the cardiovascular system, neuroprotective function, hepatoprotective activity, effects on skin diseases and so on. Based on these studies, this review focused on the research publications of A. dahurica and aimed to summarize the advances in the traditional uses, phytochemistry and pharmacology which will provide reference for the further studies and applications of A. dahurica. |
| first_indexed | 2024-04-12T09:46:05Z |
| format | Article |
| id | doaj.art-fe9813226ac7461a848eb9dbe51151ba |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-12T09:46:05Z |
| publishDate | 2022-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-fe9813226ac7461a848eb9dbe51151ba2022-12-22T03:37:57ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122022-07-011310.3389/fphar.2022.896637896637The Angelica dahurica: A Review of Traditional Uses, Phytochemistry and PharmacologyHui Zhao0Hui Zhao1Ya-Long Feng2Ming Wang3Jing-Jing Wang4Tian Liu5Tian Liu6Jun Yu7Jun Yu8Clinical Experimental Center, Xi’an International Medical Center Hospital, Xi’an, ChinaXi’an Engineering Technology Research Center for Cardiovascular Active Peptides, Xi’an, ChinaSchool of Chemistry and Chemical Engineering, Xianyang Normal University, Xianyang, ChinaCollege of Food Science and Engineering, Northwest University, Xi’an, ChinaBiomedicine Key Laboratory of Shaanxi Province, College of Life Science, Northwest University, Xi’an, ChinaClinical Experimental Center, Xi’an International Medical Center Hospital, Xi’an, ChinaXi’an Engineering Technology Research Center for Cardiovascular Active Peptides, Xi’an, ChinaClinical Experimental Center, Xi’an International Medical Center Hospital, Xi’an, ChinaXi’an Engineering Technology Research Center for Cardiovascular Active Peptides, Xi’an, ChinaAngelica dahurica (A. dahurica) root is a famous edible medicinal herb that has been used in China for thousands of years. To date, more than 300 chemical constituents have been discovered from A. dahurica. Among these ingredients, coumarins and volatile oils are the major active compounds. Moreover, a few other compounds have also been isolated from the root of A. dahurica, such as alkaloids, phenols, sterols, benzofurans, polyacetylenes and polysaccharides. Modern pharmacological studies demonstrated that the root of A. dahurica and its active components displayed various bioactivities such as anti-inflammation, anti-tumor, anti-oxidation, analgesic activity, antiviral and anti-microbial effects, effects on the cardiovascular system, neuroprotective function, hepatoprotective activity, effects on skin diseases and so on. Based on these studies, this review focused on the research publications of A. dahurica and aimed to summarize the advances in the traditional uses, phytochemistry and pharmacology which will provide reference for the further studies and applications of A. dahurica.https://www.frontiersin.org/articles/10.3389/fphar.2022.896637/fullAngelica dahuricacoumarinsimperatorinanti-inflammationanti-tumorreview |
| spellingShingle | Hui Zhao Hui Zhao Ya-Long Feng Ming Wang Jing-Jing Wang Tian Liu Tian Liu Jun Yu Jun Yu The Angelica dahurica: A Review of Traditional Uses, Phytochemistry and Pharmacology Frontiers in Pharmacology Angelica dahurica coumarins imperatorin anti-inflammation anti-tumor review |
| title | The Angelica dahurica: A Review of Traditional Uses, Phytochemistry and Pharmacology |
| title_full | The Angelica dahurica: A Review of Traditional Uses, Phytochemistry and Pharmacology |
| title_fullStr | The Angelica dahurica: A Review of Traditional Uses, Phytochemistry and Pharmacology |
| title_full_unstemmed | The Angelica dahurica: A Review of Traditional Uses, Phytochemistry and Pharmacology |
| title_short | The Angelica dahurica: A Review of Traditional Uses, Phytochemistry and Pharmacology |
| title_sort | angelica dahurica a review of traditional uses phytochemistry and pharmacology |
| topic | Angelica dahurica coumarins imperatorin anti-inflammation anti-tumor review |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2022.896637/full |
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