Betulinic acid analogs inhibit N- and T-type voltage-gated calcium channels to attenuate nerve-injury associated neuropathic and formalin models of pain

Betulinic acid analogs inhibit N- and T-type voltage-gated calcium channels to attenuate nerve-injury associated neuropathic and formalin models of pain

Over the past three decades, there has been a significant growth in the use of natural products, with approximately 80% of individuals using them for some aspect of primary healthcare. Our laboratories have identified and studied natural compounds with analgesic effects from dry land plants or their...

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Bibliographic Details
Main Authors: Aida Calderon-Rivera, Kimberly Gomez, Santiago Loya-López, E.M. Kithsiri Wijeratne, Harrison Stratton, Cheng Tang, Paz Duran, Kyleigh Masterson, Omar Alsbiei, A.A. Leslie Gunatilaka, Rajesh Khanna
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Neurobiology of Pain
Subjects:
Betulinic acid analogs
Betulin analogs
Voltage-gated calcium channels
Analgesic
Spared nerve injury mode
Formalin model
Online Access:http://www.sciencedirect.com/science/article/pii/S2452073X2300003X

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http://www.sciencedirect.com/science/article/pii/S2452073X2300003X

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