Small RNA Library Preparation Method for Next-Generation Sequencing Using Chemical Modifications to Prevent Adapter Dimer Formation.

For most sample types, the automation of RNA and DNA sample preparation workflows enables high throughput next-generation sequencing (NGS) library preparation. Greater adoption of small RNA (sRNA) sequencing has been hindered by high sample input requirements and inherent ligation side products form...

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Bibliographic Details
Main Authors: Sabrina Shore, Jordana M Henderson, Alexandre Lebedev, Michelle P Salcedo, Gerald Zon, Anton P McCaffrey, Natasha Paul, Richard I Hogrefe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5119831?pdf=render