Increased CO2 fixation enables high carbon-yield production of 3-hydroxypropionic acid in yeast

Abstract CO2 fixation plays a key role to make biobased production cost competitive. Here, we use 3-hydroxypropionic acid (3-HP) to showcase how CO2 fixation enables approaching theoretical-yield production. Using genome-scale metabolic models to calculate the production envelope, we demonstrate tha...

Full description

Bibliographic Details
Main Authors: Ning Qin, Lingyun Li, Xiaozhen Wan, Xu Ji, Yu Chen, Chaokun Li, Ping Liu, Yijie Zhang, Weijie Yang, Junfeng Jiang, Jianye Xia, Shuobo Shi, Tianwei Tan, Jens Nielsen, Yun Chen, Zihe Liu
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45557-9