The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone

The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone

Bone pain is a common complication of breast cancer (BC) bone metastasis and is a major cause of increased morbidity and mortality. Although the mechanism of BC-associated bone pain (BCABP) remains poorly understood, involvement of BC products in the pathophysiology of BCABP has been proposed. Aggre...

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Bibliographic Details
Main Authors: Tatsuo Okui, Masahiro Hiasa, Shoji Ryumon, Kisho Ono, Yuki Kunisada, Soichiro Ibaragi, Akira Sasaki, G. David Roodman, Fletcher A. White, Toshiyuki Yoneda
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Journal of Bone Oncology
Subjects:
Breast cancer
Bone pain
Sensory neurons
HMGB1
RAGE
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137420300853

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http://www.sciencedirect.com/science/article/pii/S2212137420300853

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