Identification of Somatic Mutations From Bulk and Single-Cell Sequencing Data

Somatic mutations are DNA variants that occur after the fertilization of zygotes and accumulate during the developmental and aging processes in the human lifespan. Somatic mutations have long been known to cause cancer, and more recently have been implicated in a variety of non-cancer diseases. The...

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Bibliographic Details
Main Authors: August Yue Huang, Eunjung Alice Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Aging
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2021.800380/full