Pan-Cancer Analyses Identify the CTC1-STN1-TEN1 Complex as a Protective Factor and Predictive Biomarker for Immune Checkpoint Blockade in Cancer

Pan-Cancer Analyses Identify the CTC1-STN1-TEN1 Complex as a Protective Factor and Predictive Biomarker for Immune Checkpoint Blockade in Cancer

The CTC1-STN1-TEN1 (CST) complex plays a crucial role in telomere replication and genome stability. However, the detailed mechanisms of CST regulation in cancer remain largely unknown. Here, we perform a comprehensive analysis of CST across 33 cancer types using multi-omic data from The Cancer Genom...

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Bibliographic Details
Main Authors: Lishuai Wang, Tengfei Ma, Weijin Liu, Heping Li, Zhenhua Luo, Xuyang Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Genetics
Subjects:
telomere
pan cancer
immune
prognosis
drug
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.859617/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.859617/full

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