Elevated non-esterified fatty acid concentrations during bovine oocyte maturation compromise early embryo physiology.

Elevated concentrations of serum non-esterified fatty acids (NEFA), associated with maternal disorders such as obesity and type II diabetes, alter the ovarian follicular micro-environment and have been associated with subfertility arising from reduced oocyte developmental competence. We have asked w...

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Bibliographic Details
Main Authors: Veerle Van Hoeck, Roger G Sturmey, Pablo Bermejo-Alvarez, Dimitrios Rizos, Alfonso Gutierrez-Adan, Henry J Leese, Peter E J Bols, Jo L M R Leroy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3157355?pdf=render