How is overall survival assessed in randomised clinical trials in cancer and are subsequent treatment lines considered? A systematic review

Abstract Background Overall survival is the “gold standard” endpoint in cancer clinical trials. It plays a key role in determining the clinical- and cost-effectiveness of a new intervention and whether it is recommended for use in standard of care. The assessment of overall survival usually requires...

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Bibliographic Details
Main Authors: Kara-Louise Royle, David Meads, Jennifer K. Visser-Rogers, Ian R. White, David A. Cairns
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-023-07730-1