Mechano-Sensing Channel PIEZO2 Enhances Invasive Phenotype in Triple-Negative Breast Cancer

Mechano-Sensing Channel PIEZO2 Enhances Invasive Phenotype in Triple-Negative Breast Cancer

Background: Mechanically gated PIEZO channels lead to an influx of cations, activation of additional Ca<sup>2+</sup> channels, and cell depolarization. This study aimed to investigate PIEZO2’s role in breast cancer. Methods: The clinical relevance of <i>PIEZO2</i> expression...

Full description

Bibliographic Details
Main Authors: Eriko Katsuta, Kazuaki Takabe, Marija Vujcic, Philip A. Gottlieb, Tao Dai, Arnaldo Mercado-Perez, Arthur Beyder, Qingfei Wang, Mateusz Opyrchal
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
triple-negative breast cancer
PIEZO
mechano-signaling
metastasis
Online Access:https://www.mdpi.com/1422-0067/23/17/9909

Internet

https://www.mdpi.com/1422-0067/23/17/9909

Similar Items