Persistent low level of osterix accelerates interleukin-6 production and impairs regeneration after tissue injury.

Persistent low level of osterix accelerates interleukin-6 production and impairs regeneration after tissue injury.

Osterix (Osx) is an essential transcription factor for osteoblast differentiation and bone formation. Osx knockout show a complete absence of bone formation, whereas Osx conditional knockout in osteoblasts produce an osteopenic phenotype after birth. Here, we questioned whether Osx has a potential r...

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Bibliographic Details
Main Authors: Wook-Young Baek, Seung-Yoon Park, Yeo Hyang Kim, Min-A Lee, Tae-Hwan Kwon, Kwon-Moo Park, Benoit de Crombrugghe, Jung-Eun Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724732?pdf=render

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http://europepmc.org/articles/PMC3724732?pdf=render

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