Proinflammatory and Th2 cytokines regulate the high affinity IgE receptor (FcepsilonRI) and IgE-dependant activation of human airway smooth muscle cells.

Proinflammatory and Th2 cytokines regulate the high affinity IgE receptor (FcepsilonRI) and IgE-dependant activation of human airway smooth muscle cells.

BACKGROUND:The high affinity IgE receptor (FcepsilonRI) is a crucial structure for IgE-mediated allergic reactions. We have previously demonstrated that human airway smooth muscle (ASM) cells express the tetrameric (alphabetagamma2) FcepsilonRI, and its activation leads to marked transient increases...

Полное описание

Библиографические подробности
Главные авторы: Naresh Singh Redhu, Ali Saleh, Lianyu Shan, William T Gerthoffer, Sam K Kung, Andrew J Halayko, Bouchaib Lamkhioued, Abdelilah S Gounni
Формат: Статья
Язык:English
Опубликовано: Public Library of Science (PLoS) 2009-07-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC2701636?pdf=render

Internet

http://europepmc.org/articles/PMC2701636?pdf=render

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