CD40 Ligand–CD40 Interaction Is an Intermediary between Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy

CD40 Ligand–CD40 Interaction Is an Intermediary between Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy

We aimed to investigate the role of the CD40-CD40 ligand (CD40L) pathway in inflammation-mediated angiogenesis in proliferative diabetic retinopathy (PDR). We analyzed vitreous fluids and epiretinal fibrovascular membranes from PDR and nondiabetic patients, cultures of human retinal microvascular en...

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Bibliographic Details
Main Authors: Ahmed M. Abu El-Asrar, Mohd I. Nawaz, Ajmal Ahmad, Luna Dillemans, Mairaj Siddiquei, Eef Allegaert, Priscilla W. Gikandi, Gert De Hertogh, Ghislain Opdenakker, Sofie Struyf
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
proliferative diabetic retinopathy
inflammation
angiogenesis
CD40 ligand
endothelial cells
Online Access:https://www.mdpi.com/1422-0067/24/21/15582

Internet

https://www.mdpi.com/1422-0067/24/21/15582

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