Mitochondrial Respiratory Complexes as Targets of Drugs: The PPAR Agonist Example

Mitochondrial Respiratory Complexes as Targets of Drugs: The PPAR Agonist Example

Mitochondrial bioenergetics are progressively acquiring significant pathophysiological roles. Specifically, mitochondria in general and Electron Respiratory Chain in particular are gaining importance as unintentional targets of different drugs. The so-called PPAR ligands are a class of drugs which n...

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Bibliographic Details
Main Authors: Patrizia Bottoni, Alessandro Pontoglio, Salvatore Scarà, Luisa Pieroni, Andrea Urbani, Roberto Scatena
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
mitochondria
complex I (NADH: ubiquinone oxidoreductase)
reactive oxygen species (ROS)
drug toxicity
therapeutic drug monitoring
cancer
Online Access:https://www.mdpi.com/2073-4409/11/7/1169

Internet

https://www.mdpi.com/2073-4409/11/7/1169

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