Morphological and Molecular Characterization of KRAS G12C-Mutated Lung Adenocarcinomas

Lung adenocarcinoma (LUAD) is the major subtype of non-small cell lung cancer, accounting for approximately 60% of cases. Molecular analysis of LUADs showed that the <i>KRAS</i> gene is mutated in up to 30% of cases; such cases were previously considered “undruggable”. The KRAS G12C muta...

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Bibliographic Details
Main Authors: Radu Pirlog, Nicolas Piton, Aude Lamy, Florian Guisier, Ioana Berindan-Neagoe, Jean-Christophe Sabourin, Florent Marguet
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/4/1030