Morphological and Molecular Characterization of KRAS G12C-Mutated Lung Adenocarcinomas
Lung adenocarcinoma (LUAD) is the major subtype of non-small cell lung cancer, accounting for approximately 60% of cases. Molecular analysis of LUADs showed that the <i>KRAS</i> gene is mutated in up to 30% of cases; such cases were previously considered “undruggable”. The KRAS G12C muta...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-02-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/14/4/1030 |