A cookbook for DNase Hi-C

A cookbook for DNase Hi-C

Abstract Background The Hi-C technique is widely employed to study the 3-dimensional chromatin architecture and to assemble genomes. The conventional in situ Hi-C protocol employs restriction enzymes to digest chromatin, which results in nonuniform genomic coverage. Using sequence-agnostic restricti...

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Bibliographic Details
Main Authors:	Maria Gridina, Evgeniy Mozheiko, Emil Valeev, Ludmila P. Nazarenko, Maria E. Lopatkina, Zhanna G. Markova, Maria I. Yablonskaya, Viktoria Yu Voinova, Nadezhda V. Shilova, Igor N. Lebedev, Veniamin Fishman
Format:	Article
Language:	English
Published:	BMC 2021-03-01
Series:	Epigenetics & Chromatin
Subjects:	DNAse I Hi-C Genome organization Human peripheral blood K562 LNCaP
Online Access:	https://doi.org/10.1186/s13072-021-00389-5

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