Complement C3 and Activated Fragment C3a Are Involved in Complement Activation and Anti-Bacterial Immunity

In the complement system, C3 is a central component in complement activation, immune defense and immune regulation. In all pathways of complement activation, the pivotal step is conversion of the component C3 to C3b and C3a, which is responsible to eliminate the pathogen and opsonization. In this st...

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Bibliographic Details
Main Authors: Meng Wu, Bei-bei Jia, Mo-fei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.813173/full