Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer’s Disease

Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer’s Disease

DUSP4 is a member of the DUSP (dual-specificity phosphatase) subfamily that is selective to the mitogen-activated protein kinases (MAPK) and has been implicated in a range of biological processes and functions in Alzheimer’s disease (AD). In this study, we utilized the stereotactic delivery of adeno...

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Bibliographic Details
Main Authors: Erming Wang, Allen L. Pan, Pritha Bagchi, Srikant Rangaraju, Nicholas T. Seyfried, Michelle E. Ehrlich, Stephen R. Salton, Bin Zhang
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomolecules
Subjects:
DUSP4
5xFAD
mouse model
proteomics
phosphoproteomics
MaxQuant
Online Access:https://www.mdpi.com/2218-273X/14/1/66

Internet

https://www.mdpi.com/2218-273X/14/1/66

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