Analysis of genomes and transcriptomes of clear cell renal cell carcinomas identifies mutations and gene expression changes in the TGF-beta pathway

Analysis of genomes and transcriptomes of clear cell renal cell carcinomas identifies mutations and gene expression changes in the TGF-beta pathway

The occurrence of clear cell renal cell carcinoma (ccRCC) is related to changes in the transforming growth factor-β (TGF-β) signaling pathway. In this study, we adopted an integrated approach to identify and verify the effects of changes in this pathway on ccRCC and provide a guide for identifying n...

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Bibliographic Details
Main Authors: Xiangyu Che, Jianyi Li, Yingkun Xu, Qifei Wang, Guangzhen Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Genetics
Subjects:
TGF-β
ccRCC
TCGA
prognosis
treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.953322/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.953322/full

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