Sex Hormones Promote Opposite Effects on ACE and ACE2 Activity, Hypertrophy and Cardiac Contractility in Spontaneously Hypertensive Rats.

Sex Hormones Promote Opposite Effects on ACE and ACE2 Activity, Hypertrophy and Cardiac Contractility in Spontaneously Hypertensive Rats.

<h4>Background</h4>There is growing interest in sex differences and RAS components. However, whether gender influences cardiac angiotensin I-converting enzyme (ACE) and angiotensin-converting enzyme 2 (ACE2) activity is still unknown. In the present work, we determined the relationship b...

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Bibliographic Details
Main Authors: P L M Dalpiaz, A Z Lamas, I F Caliman, R F Ribeiro, G R Abreu, M R Moyses, T U Andrade, S A Gouvea, M F Alves, A K Carmona, N S Bissoli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0127515

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https://doi.org/10.1371/journal.pone.0127515

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