Neutrophil depletion for early allogeneic islet survival in a methacrylic acid (MAA) copolymer-induced, vascularized subcutaneous space

Islet transplantation is a promising treatment for type I diabetes (T1D). Despite the high loss of islets during transplantation, current islet transplant protocols continue to rely on portal vein infusion and intrahepatic engraftment. Because of the risk of portal vein thrombosis and the loss of is...

Full description

Bibliographic Details
Main Authors: So-Yoon Won, Sean M. Kinney, Michael V. Sefton
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Transplantation
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/frtra.2023.1244093/full