Extracorporeal immune therapy with immobilized agonistic anti-Fas antibodies leads to transient reduction of circulating neutrophil numbers and limits tissue damage after hemorrhagic shock/resuscitation in a porcine model

<p>Abstract</p> <p>Background</p> <p>Hemorrhagic shock/resuscitation is associated with aberrant neutrophil activation and organ failure. This experimental porcine study was done to evaluate the effects of Fas-directed extracorporeal immune therapy with a leukocyte inhi...

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Bibliographic Details
Main Authors: Bitu-Moreno José, Baltes Jessica, Sadek Sarah, Ott Annina, Witte Ingo, Sager Martin, Paunel-Görgülü Adnana, Altrichter Jens, Lögters Tim T, Schek Alberto, Müller Wolfram, Jeri Teresa, Windolf Joachim, Scholz Martin
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Journal of Inflammation
Online Access:http://www.journal-inflammation.com/content/7/1/18