Study of Genotoxicity, Activities on Caspase 8 and on the Stabilization of the Topoisomerase Complex of Isoeleutherin and Analogues

Study of Genotoxicity, Activities on Caspase 8 and on the Stabilization of the Topoisomerase Complex of Isoeleutherin and Analogues

This study evaluated the genotoxicity of Ethanol Extract (EEEp), Dichloromethane Fraction (FDCMEp) and isoeleutherin isolated from <i>Eleutherine plicata</i>, using the micronucleus test and the impact of structural alterations on toxicity and molecular docking (topoisomerase II and DNA...

Full description

Bibliographic Details
Main Authors: Kelly Cristina Oliveira de Albuquerque, Natasha Costa da Rocha Galucio, Gleison Gonçalves Ferreira, Ana Carolina Sousa Quaresma, Valdicley Vieira Vale, Marcelo de Oliveira Bahia, Rommel Mario Rodriguez Burbano, Fábio Alberto de Molfetta, Sandro Percario, Maria Fâni Dolabela
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Molecules
Subjects:
<i>Eleutherine plicata</i>
genotoxicity
isoeleutherin
topoisomerase II
toxicity
Online Access:https://www.mdpi.com/1420-3049/28/4/1630

Internet

https://www.mdpi.com/1420-3049/28/4/1630

Similar Items