Impaired Diastolic Function Predicts Improved Ischemic Myocardial Flow by Mechanical Left Ventricular Unloading in a Swine Model of Ischemic Heart Failure

Impaired Diastolic Function Predicts Improved Ischemic Myocardial Flow by Mechanical Left Ventricular Unloading in a Swine Model of Ischemic Heart Failure

Background: Impact of mechanical left ventricular (LV) unloading on myocardial tissue perfusion and its regulating factors remain unclear. This study was conducted to elucidate the predictors of regional blood flow (RBF) improvement by mechanical LV unloading.Materials and Methods: One to four weeks...

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Bibliographic Details
Main Authors: Tomoki Sakata, Shin Watanabe, Renata Mazurek, Spyros Mavropoulos, Francisco Romeo, Kelly P. Yamada, Kiyotake Ishikawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
LV unloading
myocardial infarction
coronary blood flow
ischemia reperfusion injury
end-diastolic pressure-volume relationship
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.795322/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2021.795322/full

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