Translational Regulation by hnRNP H/F Is Essential for the Proliferation and Survival of Glioblastoma

Deregulation of mRNA translation is a widespread characteristic of glioblastoma (GBM), aggressive malignant brain tumors that are resistant to conventional therapies. RNA-binding proteins (RBPs) play a critical role in translational regulation, yet the mechanisms and impact of these regulations on c...

Full description

Bibliographic Details
Main Authors: Morgane Le Bras, Noah Gorelick, Sylvain Pautet, Betty Tyler, Stéphane Manenti, Nicolas Skuli, Stefania Millevoi, Anne Cammas
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/5/1283