Structures of the Insecticidal Toxin Complex Subunit XptA2 Highlight Roles for Flexible Domains

Structures of the Insecticidal Toxin Complex Subunit XptA2 Highlight Roles for Flexible Domains

The Toxin Complex (Tc) superfamily consists of toxin translocases that contribute to the targeting, delivery, and cytotoxicity of certain pathogenic Gram-negative bacteria. Membrane receptor targeting is driven by the A-subunit (TcA), which comprises IgG-like receptor binding domains (RBDs) at the s...

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Bibliographic Details
Main Authors: Cole L. Martin, David W. Chester, Christopher D. Radka, Lurong Pan, Zhengrong Yang, Rachel C. Hart, Elad M. Binshtein, Zhao Wang, Lisa Nagy, Lawrence J. DeLucas, Stephen G. Aller
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
TcA
toxin translocase
Cryo-EM
X-ray crystallography
Online Access:https://www.mdpi.com/1422-0067/24/17/13221

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https://www.mdpi.com/1422-0067/24/17/13221

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