Immunosuppressive landscape in hepatocellular carcinoma revealed by single-cell sequencing

Immunosuppressive landscape in hepatocellular carcinoma revealed by single-cell sequencing

Background/AimsHepatocellular carcinoma (HCC), accounting for 75-85% of primary liver cancer cases, is the third leading cause of cancer-related death worldwide. The purpose of this research was to examine the tumor immune microenvironment (TIME) in HCC.MethodsWe investigated the HCC TIME by integra...

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Bibliographic Details
Main Authors: Yi Bai, Dapeng Chen, Chuanliang Cheng, Zhongmin Li, Hao Chi, Yuliang Zhang, Xiaoyu Zhang, Shaohai Tang, Qiang Zhao, Bing Ang, Yamin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
primary liver cancer
hepatocellular carcinoma
single cell sequencing
tumor immune microenvironment
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.950536/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.950536/full

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