Sprouty1 is a broad mediator of cellular senescence

Abstract Genes of the Sprouty family (Spry1-4) restrain signaling by certain receptor tyrosine kinases. Consequently, these genes participate in several developmental processes and function as tumor suppressors in adult life. Despite these important roles, the biology of this family of genes still r...

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Bibliographic Details
Main Authors: Carlos Anerillas, Aida Perramon-Güell, Gisela Altés, Sara Cuesta, Marta Vaquero, Anna Olomí, Ruth Rodríguez-Barrueco, David Llobet-Navàs, Joaquim Egea, Xavi Dolcet, Andrée Yeramian, Mario Encinas
Format: Article
Language:English
Published: Nature Publishing Group 2024-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06689-4