Chronic wasting disease in bank voles: characterisation of the shortest incubation time model for prion diseases.

In order to assess the susceptibility of bank voles to chronic wasting disease (CWD), we inoculated voles carrying isoleucine or methionine at codon 109 (Bv109I and Bv109M, respectively) with CWD isolates from elk, mule deer and white-tailed deer. Efficient transmission rate (100%) was observed with...

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Bibliographic Details
Main Authors: Michele Angelo Di Bari, Romolo Nonno, Joaquín Castilla, Claudia D'Agostino, Laura Pirisinu, Geraldina Riccardi, Michela Conte, Juergen Richt, Robert Kunkle, Jan Langeveld, Gabriele Vaccari, Umberto Agrimi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3591354?pdf=render