Experimental and Computational Evaluation of Chloranilic Acid as an Universal Chromogenic Reagent for the Development of a Novel 96-Microwell Spectrophotometric Assay for Tyrosine Kinase Inhibitors

Experimental and Computational Evaluation of Chloranilic Acid as an Universal Chromogenic Reagent for the Development of a Novel 96-Microwell Spectrophotometric Assay for Tyrosine Kinase Inhibitors

The tyrosine kinase inhibitors (TKIs) are chemotherapeutic drugs used for the targeted therapy of various types of cancer. This work discusses the experimental and computational evaluation of chloranilic acid (CLA) as a universal chromogenic reagent for developing a novel 96-microwell spectrophotome...

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Bibliographic Details
Main Authors: Ibrahim A. Darwish, Hany W. Darwish, Nasr Y. Khalil, Ahmed Y. A. Sayed
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
tyrosine kinase inhibitors
chloranilic acid
charge-transfer reaction
96-microwell spectrophotometric assay
high-throughput pharmaceutical analysis
Online Access:https://www.mdpi.com/1420-3049/26/3/744

Internet

https://www.mdpi.com/1420-3049/26/3/744

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