Human carboxylesterase 2: Studies on the role of glycosylation for enzymatic activity

Human carboxylesterase 2: Studies on the role of glycosylation for enzymatic activity

Human carboxylesterase 2 (hCES2) is a glycoprotein involved in the metabolism of drugs and several environmental xenobiotics, whose crystallization has been proved to be a challenging task. This limitation could partly be due to glycosylation heterogeneity and has delayed the disclosure of the 3D st...

Full description

Bibliographic Details
Main Authors: Márcia Alves, Joana Lamego, Tiago Bandeiras, Rute Castro, Hélio Tomás, Ana Sofia Coroadinha, Júlia Costa, Ana Luisa Simplício
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Carboxylesterase
Deglycosylation
Glycosylation
hCES
Site directed mutagenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580815001387

Internet

http://www.sciencedirect.com/science/article/pii/S2405580815001387

Similar Items