Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants
Saville, Mannar et al. provide a structural basis for enhanced antibody evasion and ACE2 binding by the Delta SARS-CoV-2 spike protein. They further identify a head-to-head dimer-of-trimers cryoEM reconstruction unique to the Kappa variant spike.
Bibliographic Details
| Main Authors: |
James W. Saville,
Dhiraj Mannar,
Xing Zhu,
Shanti S. Srivastava,
Alison M. Berezuk,
Jean-Philippe Demers,
Steven Zhou,
Katharine S. Tuttle,
Inna Sekirov,
Andrew Kim,
Wei Li,
Dimiter S. Dimitrov,
Sriram Subramaniam |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-02-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-022-28324-6
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