Olanzapine-induced lipid disturbances: A potential mechanism through the gut microbiota-brain axis

Objective: Long-term use of olanzapine can induce various side effects such as lipid metabolic disorders, but the mechanism remains to be elucidated. The gut microbiota-brain axis plays an important role in lipid metabolism, and may be related to the metabolic side effects of olanzapine. Therefore,...

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Bibliographic Details
Main Authors: Zhenyu Zhu, Yuxiu Gu, Cuirong Zeng, Man Yang, Hao Yu, Hui Chen, Bikui Zhang, Hualin Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.897926/full