Voltage-Gated Na<sup>+</sup> Channels in Alzheimer’s Disease: Physiological Roles and Therapeutic Potential

Voltage-Gated Na<sup>+</sup> Channels in Alzheimer’s Disease: Physiological Roles and Therapeutic Potential

Alzheimer’s disease (AD) is the most common cause of dementia and is classically characterized by two major histopathological abnormalities: extracellular plaques composed of amyloid beta (Aβ) and intracellular hyperphosphorylated tau. Due to the progressive nature of the disease, it is of the utmos...

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Bibliographic Details
Main Authors: Timothy J. Baumgartner, Zahra Haghighijoo, Nana A. Goode, Nolan M. Dvorak, Parsa Arman, Fernanda Laezza
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Life
Subjects:
voltage-gated sodium channels
Alzheimer’s disease
excitability
hippocampus
neurodegeneration
plasticity
Online Access:https://www.mdpi.com/2075-1729/13/8/1655

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https://www.mdpi.com/2075-1729/13/8/1655

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