Glucose Reduction Prevents Replicative Senescence and Increases Mitochondrial Respiration in Human Mesenchymal Stem Cells
The unique self-renewal and multilineage differentiation potential of mesenchymal stem cells (MSCs) make them a promising candidate for cell therapy applications. However, during in vitro expansion of MSCs, replicative senescence may occur and will compromise the quality of the expanded cells. Becau...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2011-07-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368910X539100 |