Glucose Reduction Prevents Replicative Senescence and Increases Mitochondrial Respiration in Human Mesenchymal Stem Cells

The unique self-renewal and multilineage differentiation potential of mesenchymal stem cells (MSCs) make them a promising candidate for cell therapy applications. However, during in vitro expansion of MSCs, replicative senescence may occur and will compromise the quality of the expanded cells. Becau...

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Bibliographic Details
Main Authors: Ting Lo, Jennifer H. Ho, Muh-Hwa Yang, Oscar K. Lee M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2011-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368910X539100