Expanding chemical space by para-C−H arylation of arenes
Biaryls are privileged structural motif used in the discovery and design of therapeutics with high affinity and specificity for a broad range of protein targets. Herein, the authors develop a robust strategy for para-C–H arylation of arenes with a range of (het)aryl iodides, including bioactive mole...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-31506-x |