Baclofen-associated neurophysiologic target engagement across species in fragile X syndrome

Baclofen-associated neurophysiologic target engagement across species in fragile X syndrome

Abstract Background Fragile X syndrome (FXS) is the most common inherited form of neurodevelopmental disability. It is often characterized, especially in males, by intellectual disability, anxiety, repetitive behavior, social communication deficits, delayed language development, and abnormal sensory...

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Bibliographic Details
Main Authors: Carrie R. Jonak, Ernest V. Pedapati, Lauren M. Schmitt, Samantha A. Assad, Manbir S. Sandhu, Lisa DeStefano, Lauren Ethridge, Khaleel A. Razak, John A. Sweeney, Devin K. Binder, Craig A. Erickson
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Journal of Neurodevelopmental Disorders
Subjects:
Fragile X syndrome
Electroencephalography
Biomarker
Baclofen
Autism
Multielectrode array
Online Access:https://doi.org/10.1186/s11689-022-09455-9

Internet

https://doi.org/10.1186/s11689-022-09455-9

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