Gypenoside XVII, an Active Ingredient from Gynostemma Pentaphyllum, Inhibits C3aR-Associated Synaptic Pruning in Stressed Mice

Gypenoside XVII, an Active Ingredient from Gynostemma Pentaphyllum, Inhibits C3aR-Associated Synaptic Pruning in Stressed Mice

Gynostemma pentaphyllum is a herbal medicine widely used in Asian countries, and its saponin extracts have been shown to possess potent anti-inflammatory effects. Gypenoside XVII, an active ingredient isolated from Gynostemma pentaphyllum, has been found to alleviate the inflammation induced by LPS...

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Bibliographic Details
Main Authors: Man-Man Zhang, Guo-Ming Huo, Jie Cheng, Qiu-Ping Zhang, Na-Zhi Li, Min-Xia Guo, Qing Liu, Guang-Hui Xu, Ji-Xiao Zhu, Cheng-Fu Li, Feng Zhou, Li-Tao Yi
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Nutrients
Subjects:
Gypenoside XVII
antidepressant
complement C3
synaptic pruning
microglia
Online Access:https://www.mdpi.com/2072-6643/14/12/2418

Internet

https://www.mdpi.com/2072-6643/14/12/2418

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