Ginsenoside F1 Ameliorates Endothelial Cell Inflammatory Injury and Prevents Atherosclerosis in Mice through A20-Mediated Suppression of NF-kB Signaling

Ginsenoside F1 Ameliorates Endothelial Cell Inflammatory Injury and Prevents Atherosclerosis in Mice through A20-Mediated Suppression of NF-kB Signaling

Atherosclerosis (AS) is a chronic inflammatory disease and endothelial cell injury is the initial event. In this study, we investigated the protective effects of ginsenoside F1 (GF1) on AS and the potential molecular mechanisms of ox-LDL induced endothelial injury. ApoE-/- mice were fed a high fat d...

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Bibliographic Details
Main Authors: Meng Qin, Yun Luo, Shan Lu, Jing Sun, Ke Yang, Guibo Sun, Xiaobo Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Pharmacology
Subjects:
Ginsenoside F1
ox-LDL
HUVECs
inflammatory injury
A20
atherosclerosis
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00953/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00953/full

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