In Vitro and In Vivo Anti-<i>Candida</i> Activity and Structural Analysis of Killer Peptide (KP)-Derivatives

In Vitro and In Vivo Anti-<i>Candida</i> Activity and Structural Analysis of Killer Peptide (KP)-Derivatives

The previously described decapeptide AKVTMTCSAS (killer peptide, KP), derived from the variable region of a recombinant yeast killer toxin-like anti-idiotypic antibody, proved to exert a variety of antimicrobial, antiviral, and immunomodulatory activities. It also showed a peculiar self-assembly abi...

Full description

Bibliographic Details
Main Authors: Tecla Ciociola, Thelma A. Pertinhez, Tiziano De Simone, Walter Magliani, Elena Ferrari, Silvana Belletti, Tiziana D’Adda, Stefania Conti, Laura Giovati
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Journal of Fungi
Subjects:
antifungal peptides
<i>Candida albicans</i>
circular dichroism spectroscopy
confocal microscopy
electron microscopy
<i>Galleria mellonella</i> model
Online Access:https://www.mdpi.com/2309-608X/7/2/129

Internet

https://www.mdpi.com/2309-608X/7/2/129

Similar Items