Identification of the H3K36me3 reader LEDGF/p75 in the pancancer landscape and functional exploration in clear cell renal cell carcinoma

Identification of the H3K36me3 reader LEDGF/p75 in the pancancer landscape and functional exploration in clear cell renal cell carcinoma

Lens epithelium-derived growth factor (LEDGF/p75) is a reader of epigenetic marks and a potential target for therapeutic intervention. Its involvement in human immunodeficiency virus (HIV) integration and the development of leukemia driven by MLL (also known as KMT2A) gene fusion make it an attracti...

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Bibliographic Details
Main Authors: Yuwei Zhang, Wei Guo, Yangkun Feng, Longfei Yang, Hao Lin, Pengcheng Zhou, Kejie Zhao, Lin Jiang, Bing Yao, Ninghan Feng
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
LEDGF/p75
H3K36me3
Pancancer
SETD2
Clear cell renal cell carcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037023002982

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http://www.sciencedirect.com/science/article/pii/S2001037023002982

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