A Bibenzyl Component Moscatilin Mitigates Glycation-Mediated Damages in an SH-SY5Y Cell Model of Neurodegenerative Diseases through AMPK Activation and RAGE/NF-<i>κ</i>B Pathway Suppression
Moscatilin can protect rat pheochromocytoma cells against methylglyoxal-induced damage. Elimination of the effect of advanced glycation end-products (AGEs) but activation of AMP-activated protein kinase (AMPK) are the potential therapeutic targets for the neurodegenerative diseases. Our study aimed...
Main Authors: | Mei Chou Lai, Wayne Young Liu, Shorong-Shii Liou, I-Min Liu |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/19/4574 |
Similar Items
-
Moscatilin suppresses the inflammation from macrophages and T cells
by: Zhang Ying, et al.
Published: (2022-04-01) -
The Citrus Flavonoid Hesperetin Encounters Diabetes-Mediated Alzheimer-Type Neuropathologic Changes through Relieving Advanced Glycation End-Products Inducing Endoplasmic Reticulum Stress
by: Mei-Chou Lai, et al.
Published: (2022-02-01) -
Docking and ADMET studies for investigating the anticancer potency of Moscatilin on APC10/DOC1 and PKM2 against five clinical drugs
by: Ipsita Pujari, et al.
Published: (2021-10-01) -
Human coculture model of astrocytes and SH-SY5Y cells to test the neurotoxicity of chemicals
by: Seungmin Park, et al.
Published: (2024-01-01) -
Irreversible methadone-induced GSTP1 downregulation in SH-SY5Y cells
by: Khyber Saify, et al.
Published: (2024-03-01)