Itraconazole Loaded Biosurfactin Micelles with Enhanced Antifungal Activity: Fabrication, Evaluation and Molecular Simulation

Itraconazole Loaded Biosurfactin Micelles with Enhanced Antifungal Activity: Fabrication, Evaluation and Molecular Simulation

Itraconazole (ITZ) is a broad-spectrum antifungal for superficial subcutaneous and systemic fungal infections. This study aimed to enhance the antifungal activity of ITZ using surfactin A (SA), a cyclic lipopeptide produced by the SA-producing <i>Bacillus</i> strain NH-100, possessing st...

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Bibliographic Details
Main Authors: Faisal Usman, Mudassir Farooq, Tanveer A. Wani, Hassan Ahmad, Ibrahim Javed, Mazhar Iqbal, Fatima Akbar Sheikh, Farhan Siddique, Seema Zargar, Saleh Sheikh
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Antibiotics
Subjects:
itraconazole
micelles
surfactin A
hemolysis
molecular simulation
Online Access:https://www.mdpi.com/2079-6382/12/10/1550

Internet

https://www.mdpi.com/2079-6382/12/10/1550

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